We have recently utilized a patient diary for COPD exacerbation monitoring in collaboration with AstraZeneca. The patient diary or electronic Patient Reported Outcome (ePRO) solution utilized the EXAcerbations of Chronic pulmonary disease Tool (EXACT) to detect COPD exacerbations. The patient diary was delivered to a smartphone device daily for the patient to complete.
Smartphone data collection proved to be an efficient method for collecting patient diary data directly from patients, which is demonstrated by high diary compliance of 95.4%. This combats the common misconception that older populations are not tech savvy and have trouble complying to electronic diaries, since the patients in this trial ranged from 48 to 88 years of age. Furthermore, an algorithm was setup to detect symptom progression toward exacerbation and automatically raise a flag and notify the physician to follow up with the patient. Detailed information can be found in the following article:
A randomised controlled trial of the effect of automated interactive calling combined with a health risk forecast on frequency and severity of exacerbations of COPD assessed clinically and using EXACT PRO
*David MG Halpina, Tish Laing-Mortonb, Sarah Speddingb, Mark L Levyc, Peter Coyled, Jonathan Lewise, Paul Newbolde, Penny Marnob
HealthDiary provides Electronic Data Capture (EDC), Patient Diaries (ePRO) and Patient Registry services to Biopharma and CRO organizations. To learn more about our services, please contact us today.